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Substance Profile
Tetrahydroharmine (THH) is a beta-carboline alkaloid and the most abundant active compound in Banisteriopsis caapi. It is a weak reversible MAO-A inhibitor but a potent serotonin reuptake inhibitor (SRI). This unique dual action contributes significantly to the empathogenic and mood-elevating character of ayahuasca. THH extends DMT's duration not only through MAO inhibition but also modulates the serotonergic system directly via serotonin reuptake.
No subjective effects data available yet.
No linked studies yet.