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Substance Profile
Scopolamine (hyoscine) is a naturally occurring tropane alkaloid from plants of the nightshade family (Datura, Brugmansia, Hyoscyamus). It acts as a competitive antagonist at muscarinic acetylcholine receptors, producing delirium-like states with complete loss of reality contact at high doses. Medically, scopolamine is used in low doses as an antiemetic and for motion sickness. Recent research investigates sub-deliriant doses as a rapid-acting antidepressant through cholinergic pathways.
No subjective effects data available yet.
No linked studies yet.