Get a weekly digest of the latest psychedelic research, new studies, and platform updates delivered to your inbox.
No spam, ever. Unsubscribe anytime.
Substance Profile
Muscarine is a quaternary ammonium compound found in small amounts in Amanita muscaria, but in significantly higher concentrations in other mushrooms such as Clitocybe dealbata and Inocybe species. It is a selective muscarinic acetylcholine receptor agonist producing cholinergic symptoms (sweating, salivation, bradycardia, miosis). In A. muscaria, muscarine content is low enough not to cause significant toxicity; the primary effects of A. muscaria are mediated by muscimol and ibotenic acid. However, in Clitocybe or Inocybe poisoning, muscarine can produce life-threatening symptoms. Historically, muscarine gave its name to the entire class of muscarinic receptors.
Non-selective mAChR agonist; activates M1-M5 receptors producing parasympathomimetic effects
No subjective effects data available yet.
No linked studies yet.